Nr2c2 | nuclear receptor subfamily 2, group C, member 2

GeneMGI:1352466Synonyms: TAK1, Tr4

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	3 supporting datasets	Nr2c2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Nr2c2^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
impaired glucose tolerance	1 supporting dataset	Nr2c2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.26x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nr2c2.

Associated images

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Histopathology

There is no histopathology data found for Nr2c2.

IMPC related publications

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External links

No external links available for Nr2c2.

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*Nr2c2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Nr2c2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nr2c2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nr2c2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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